Using a modular massively parallel reporter assay to discover context-dependent regulatory activity in type 2 diabetes-linked noncoding regions.

HGG Adv · 2026 · PMC13125165 · PMID 41952336

Europe PMC DOI

hedged sentence

0.0556

closest p · 1.1× alpha

0.0556

boldest claim

The sentences

nearly significantp = 0.05556so close (0.05 < p ≤ 0.1)

There is a nearly significant difference (Wilcoxon rank-sum test p = 0.05556) between the oligo with the HNF1 motif deleted compared to the intact, reference allele oligo; however, the oligo with the HNF1 motif deleted displayed high variance in activity ( Figure S6 A).

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