From chain length to cell death: mechanistic basis for ROS-mediated apoptosis induced by saturated fatty acids.

Sci Rep · 2026 · PMC13125287 · PMID 41844847

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a clear trendno p-value reported

For PC-3 cells, the IC 50 values ranged from 18.4 μM (C18-MEA) to 645.9 μM (C8-MEA), showing a clear trend where longer-chain fatty acids (C18-MEA) exhibited the highest cytotoxicity, while C8-MEA was much less effective.

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