Dosimetric Correlates of Acute Toxicities for Moderate Hypofractionated Whole-Breast Irradiation: Implications for ASTRO Planning Guidelines.

Adv Radiat Oncol · 2026 · PMC13126266 · PMID 42063412

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Multivariate analysis, showed a trend toward decreased grade ≥ 2 acute skin toxicity with hypofractionation and the study concluded this to be likely due to smaller V105% volumes with hypofractionation recommending therefore to keep the V105% for the whole-breast plan <50 cm 3 .

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