Measuring thyroid-stimulating hormone receptor antibodies using the IMMULITE<sup>®</sup> 2000 TSI assay is better than using the BRAHMS TRAK assay in an unselected clinical population, but both perform worse than expected: a real-world retrospective observational study.

Thyroid Res · 2026 · PMC13126691 · PMID 42050714

Europe PMC DOI

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The sentences

showed a trendp = 0.07so close (0.05 < p ≤ 0.1)

ROC AUCs showed that TRAb-KR had no ability to predict recurrence (0.57, 95% CI 0.41–0.73; p = 0.40), which is why no appropriate cut-off could be determined, whereas TRAb-IM showed a trend towards correlation with recurrence (0.65, 95% CI 0.47–0.82; p = 0.07), even though not reaching statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Measuring thyroid-stimulating hormone receptor antibodies using the IMMULITE&lt;sup&gt;®&lt;/sup&gt; 2000 TSI assay is better than using the BRAHMS TRAK assay in an unselected clinical population, but both perform worse than expected: a real-world retrospective observational study.

The sentences

Measuring thyroid-stimulating hormone receptor antibodies using the IMMULITE<sup>®</sup> 2000 TSI assay is better than using the BRAHMS TRAK assay in an unselected clinical population, but both perform worse than expected: a real-world retrospective observational study.