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Benzodiazepine or Z-hypnotic use during pregnancy and risk of psychiatric disorders in children: population based cohort study.

BMJ · 2026 · PMC13126849 · PMID 42055584

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Overall, Z-hypnotic exposure was also associated with a slightly elevated estimate (versus unexposed: hazard ratio 1.22, 1.13 to 1.31; sibling controlled: 1.12, 0.94 to 1.33), particularly for durations exceeding 30 days (versus unexposed: hazard ratio 1.15, 1.01 to 1.30; sibling controlled: 1.31, 0.96 to 1.78), although these findings did not reach statistical significance.

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