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The Alpha-1 Pi*MZ Genotype Is an Independent Risk Factor for Hepatocellular Carcinoma Development in Patients With ACLD.

Aliment Pharmacol Ther · 2026 · PMC13127851 · PMID 41577636

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showed a trendno p-value reported
Interestingly, the Pi * MZ genotype was the only SNV statistically significantly associated with HCC development during follow‐up in our study, as PNPLA3 only showed a trend in our longitudinal analysis.

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