The Causal Relationship between Blood Cell Traits and Valvular Heart Disease: A Two-Sample Mendelian Randomization Study.

Arq Bras Cardiol · 2026 · PMC13128221 · PMID 42138859

Europe PMC DOI

hedged sentence

0.1600

closest p · 3.2× alpha

0.1600

boldest claim

The sentences

did not reach statistical significancep = 0.16not close (p > 0.1)

Although the weighted median did not reach statistical significance (OR = 0.61, 95% CI: 0.31-1.20, p = 0.16) ( Table 1 ), the MR-Egger estimate supported this association (OR = 0.48, 95% CI: 0.26-0.90, p = 0.02) ( Table 1 ).

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