Stroke progression index as a dynamic metric is associated with functional outcome in progressive ischemic stroke with large vessel occlusion.

Front Neurol · 2026 · PMC13128660 · PMID 42079818

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did not reach statistical significanceno p-value reported

Interaction analysis between SPI and anterior circulation After anterior circulation occlusion was included as a covariate in the multivariable model, age ( p = 0.025), SPI (OR 1.269; 95% CI 1.133–1.421; p < 0.001), anterior circulation occlusion (OR 3.589; 95% CI 1.491–8.640; p = 0.004), and EVT (OR 0.300; 95% CI 0.143–0.629; p = 0.001) were independently associated with poor outcome, whereas Δ t did not reach statistical significance ( Supplementary Table 3 ).

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a decreasing trendno p-value reported

Overall, ARR showed a decreasing trend with increasing SPI values.

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