The 5-HT1A receptor antagonist WAY-100635 maleate promotes retinal ganglion cell differentiation and protects the retino-visual circuits.

In untreated mice, the glaucomatous eye preserved cortical responses but showed a trend of early (day 9) hyperexcitability, through increased P1-N1 peak-to-peak amplitude and a larger negative area under the curve (AUC) which remained unaffected by WAY treatment (Fig. 7l, m, n ).

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