First-line PD-1 inhibitor plus chemotherapy improves outcomes in advanced gastric cancer and correlates with specific biomarkers in a real-world cohort.

Discov Oncol · 2026 · PMC13129140 · PMID 41863740

Europe PMC DOI

hedged sentence

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

did not reach statistical significancep = 0.058so close (0.05 < p ≤ 0.1)

For OS, HER2 expression showed a similar negative trend but did not reach statistical significance (adjusted HR = 1.27, 95% CI: 0.99–1.62, p = 0.058).

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