Integrating intracranial hypofractionated radiotherapy with immunotherapy for melanoma brain metastases: therapeutic impact and immune modulation.

Ther Adv Med Oncol · 2026 · PMC13129331 · PMID 42077607

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a notable trendno p-value reported

Furthermore, in patients with varying RECIST responses, M-CSF, IL-18, CXCL9, and CXCL10 expression levels showed a notable trend.

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nominally significantno p-value reported

Post-treatment, several cytokines, predominantly proinflammatory and chemotactic factors, showed nominally significant increases.

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