Transcriptomic signatures of high‑intensity pyrethroid resistance in Anopheles gambiae from a Cameroonian agricultural hotspot.

BMC Genomics · 2026 · PMC13130547 · PMID 41872752

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0500

boldest claim

The sentences

highly significantp < 0.001actually significant

Fisher’s exact tests confirmed highly significant contrasts for these variants (Man_R-S and Man_C-S, p < 0.001).

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did not reach statistical significancep > 0.05actually significant

However, differences relative to dsGFP controls did not reach statistical significance ( p > 0.05).

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an increasing trendno p-value reported

Moreover, multiple studies have documented an increasing trend of pyrethroid resistance, with mosquitoes increasingly surviving exposure to concentrations exceeding ten times the diagnostic dose [ 6 , 7 , 14 ] or enduring prolonged contact times [ 15 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.