Pre-Human Immunodeficiency Virus (HIV) infection Th17 CD4+ T cells as predictors of early HIV disease progression.

PLoS Pathog · 2026 · PMC13132424 · PMID 42030410

Europe PMC DOI

hedged sentence

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

did not reach statistical significancep = 0.057so close (0.05 < p ≤ 0.1)

When data from both cohorts were combined, higher pre-HIV IL-17-producing CD4 + T cell frequencies were associated with faster CD4 decline in the unadjusted model (HR = 2.2, 95% CI: 1.1 – 4.3, p = 0.023) but did not reach statistical significance in the adjusted model (aHR = 2.2, 95% CI: 0.9 – 5.0, p = 0.057; Fig 4C ).

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