The FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle.

Elife · 2026 · PMC13132546 · PMID 42059432

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Fam53C -/- and Fam53C +/- mice were recovered at the expected frequency from Fam53C +/- crosses in the IMPC colony (with a low number of mice analyzed, Figure 6—figure supplement 1A ), but with a significant trend towards fewer of the homozygous mutant mice in our colony at Stanford University (with more mice analyzed, Figure 6B ).

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