Barely Significant
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Oxidative stress mechanisms and potential biomarkers of methyl acetate poisoning: a urinary metabolomics study in rat model and human occupational cohort.

Front Mol Biosci · 2026 · PMC13132698 · PMID 42077562

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a numerical increasing trendno p-value reported
Among them, the methanol concentration in the MMA group was significantly higher than that in the LMA group, while no statistically significant difference was found between the HMA and MMA groups, despite a numerical increasing trend ( Figure 1B ).

also in 13 other papers

a decreasing trendno p-value reported
Rat body weight, methanol/formic acid levels in blood and eyeballs, and retinal histological changes After 3 days of MA exposure, there was no statistically significant difference in body weight gain between MA-exposed groups (low-dose LMA, medium-dose MMA, high-dose HMA) and the control group, but a decreasing trend was observed in the MA-exposed groups ( Figure 1A ).

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