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Antimicrobial peptide-induced inner membrane hyperpolarization is associated with antibiotic sensitization and attenuated MIC escalation in multidrug-resistant Gram-negative pathogens.

NPJ Antimicrob Resist · 2026 · PMC13133131 · PMID 42062577

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7f ), which was numerically lower than TP2-5 monotherapy but higher than colistin alone (75%) and did not reach statistical significance compared to the TP2-5 alone group, suggesting that this difference reflects individual animal variability rather than a true antagonistic interaction.

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