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The role of circular RNAs as miRNA sponges in the mechanisms and therapeutic potential of triple negative breast cancer.

Discov Oncol · 2026 · PMC13133293 · PMID 41870705

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​ In liquid biopsies, circTRPS1 was identified to be higher in cancer plasma when compared with normal controls (showing a tendency towards significance) and it occurred significantly more often in ER-negative BC [ 66 ]. ​ Other plasma circRNAs such as circVAV3, circDNAH14, and circCDYL were also higher in cancer tissues compared to normal ones, with circERBB2 and circCDYL significantly correlating with metastatic disease [ 66 ]. ​A diagnostic mode

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