Efficacy, safety, and completion of modified short-course rifapentine and isoniazid for latent tuberculosis infection in patients with high-risk rheumatic disease: a multicentre, open-label, randomized, non-inferiority trial.

EClinicalMedicine · 2026 · PMC13133530 · PMID 42077650

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did not reach statistical significanceno p-value reported

The proportion of patients with adverse events related to preventive drugs was 9.6% (24/249) in the 3HP-PUMCH group and 15.0% (39/260) in the 9H group (p = 0.066), Although the proportion of drug-related adverse events was numerically lower in the 3HP-PUMCH group, this difference did not reach statistical significance.

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