5B ), which showed that, while all single and double WW domain deletions in combination with WBP2 showed a trend towards decreased β-galactosidase activity as compared to the wild-type WWP1, only the ΔWW1+3/WBP2 combination displayed a statistically significant decrease in reporter gene expression that was comparable to that of the negative controls.
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Identification and validation of an interaction between the E3 ubiquitin ligase WWP1 and the Transcriptional Co-Activator WBP2 in the human heart.
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