The Overlooked Autoantibody Repertoire: Exploring the Biomarker Potential of Downregulated Autoantibodies in NSCLC.

As shown in Figure S6 , four AAbs significantly increased postoperatively ( p < 0.05), while anti‐CAMKK2 AAb showed a trend toward increase ( p = 0.069), suggesting that the downregulation of these AAbs was likely associated with the tumor presence. 3.5 Prognostic Risk Assessment and Model Construction Based‐On Downregulated AAbs To identify key variables for the prognostic model, we employed LASSO Cox regression with 10‐fold cross‐validation to identify risk variables and determine their coefficients (Figure S7A,B ).

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