Metformin for preventing esophageal stricture after circumferential endoscopic submucosal dissection in a canine model.

Gastroenterol Rep (Oxf) · 2026 · PMC13134663 · PMID 42079394

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Conclusion Metformin effectively promoted esophageal wound re-epithelialization after ESD, reduced submucosal fibrosis, and showed a trend toward alleviating esophageal stricture. animal experimentation esophageal stricture endoscopic submucosal dissection fibrosis metformin Intra-hospital Project at 900th Hospital of PLA Joint Logistic Support Force 2022MS34 Startup Fund for scientific research, Fujian Medical University 2020

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