Preoperative 15 mg of melatonin for reducing anxiety and post-traumatic stress disorder symptoms in mandibular third molar surgery: A randomized double-blind placebo-controlled clinical trial.

Med Oral Patol Oral Cir Bucal · 2026 · PMC13135289 · PMID 41578909

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

did not reach statistical significancep=0.060so close (0.05 < p ≤ 0.1)

At baseline, the mean DSST score was lower in melatonin group (54.1±9.5) compared to placebo group (59.7±10.5), a difference that approached but did not reach statistical significance (Student t test, p=0.060).

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