Atypical memory B cell clonal expansion and inflammatory programs associate with platelet-activating antibody development in COVID-19.

Although all the tested cytokines trended toward an increase in PEA + patients, IL-2 and CCL5 were the only ones that reached significance, with IL-12 and CXCL10 nearing significance at P = 0.0519 and 0.0524, respectively ( Figure 6C ).

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Flow cytometry analysis yielded similar findings, with modest variation between the 2 COVID-19 patient cohorts that did not reach statistical significance ( Figure 1, F and G , and Supplemental Figure 1G ).

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