Assessment of radiotherapy effect and toxicity using tissue-associated DNA methylation markers in cell-free DNA: a study on prostate cancer.

Radiat Environ Biophys · 2026 · PMC13135590 · PMID 41790195

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did not reach statistical significancep > 0.05actually significant

Although serum mtDNA-79 and mtDNA-230 levels in the Pre-RT group were higher than those in the Control group, these differences did not reach statistical significance (both p > 0.05) (Figs. 1 and 2 ). mtDNA integrity, defined as the ratio of long to short mtDNA fragments, was evaluated in the Control, Pre-RT, and Post-RT groups.

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