Clinical Feasibility of Early First-Trimester Non-Invasive Prenatal Testing: Associations Between Gestational Age, Fetal Fraction, and No-Call Rates.

Appl Clin Genet · 2026 · PMC13135759 · PMID 42083549

Europe PMC DOI

hedged sentence

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

did not reach statistical significancep = 0.053so close (0.05 < p ≤ 0.1)

Maternal age showed a weak inverse association with FF; however, this relationship did not reach statistical significance (β = −0.02; 95% CI, −0.04 to 0.00; p = 0.053).

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