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Evaluation of dnDSA risk stratification using the updated PIRCHE-T2 model in two kidney transplant cohorts.

Front Immunol · 2026 · PMC13135921 · PMID 42088492

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The updated model showed significantly better separation between >14.8 and ≤14.8 score groups in Zurich (p = 0.025) and in the combined dataset (p = 0.005), whereas the old model failed to reach statistical significance in any cohort.

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