Integrated transcriptomic and single cell analysis combined with artificial neural network identifies a robust gene signature for early discrimination of MASL and MASH.

Front Immunol · 2026 · PMC13135947 · PMID 42088521

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did not reach statistical significanceno p-value reported

Independent validation in the GSE135251 cohort confirmed increased expression of MMP9, FABP5 , TREM2 , and UBD and reduced expression of MAP2K1 , while CTSD did not reach statistical significance, as shown in Figure 5D .

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