Feature representation for explainable CRISPR off-target prediction and base editing efficiency.

Front Bioinform · 2026 · PMC13136712 · PMID 42088116

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

a clear trendno p-value reported

The ALE plot reveals a clear trend: even small numbers of mismatches (distance 1–2) produce a measurable negative effect on the predicted score, which intensifies sharply as the distance increases.

also in 19,460 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.