Quantitative analysis confirmed a significant reduction in cortical infarct volume in the 60 mg/kg group (vehicle: 24.2 ± 5.4 mm 3 ; CHD 60 mg/kg: 16.6 ± 4.8 mm 3 ; p < 0.05), while both 30 mg/kg and 120 mg/kg groups also showed a trend toward decreased infarct volume compared with vehicle ( Figures 2A,B ).
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Chunghyul-dan, a multi-botanical ethanol extract, improves collateral perfusion and neurovascular stability in permanent focal cerebral ischemia.
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