A decade of change: trends in drug and alcohol use in Iran (2010-2019).

Opium use declined by 4.3%, while heroin and drug injection showed an increasing trend from 2013 to 2016, followed by a decline from 2016 to 2019.

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The sensitivity analysis results (Table S2 and Figure S1 ) showed a trend similar to that in Fig. 1 (which used the original correction factors), demonstrating the robustness of the findings despite changes in the correction factors.

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