Duhuo Jisheng Decoction ameliorates experimental intervertebral disc degeneration by modulating immune-inflammatory responses through regulation of macrophage polarization.

Front Immunol · 2026 · PMC13138942 · PMID 42093971

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showed a trendno p-value reported

The aggrecan and collagen 2 of the DHJSD treatment group were significantly better than those of the model group at the same time point, and the in vivo inflammatory factors IL-5, IL-1β, and TNF-α, as well as MMP13 and MMP2, showed a trend contrary to that of the ECM.

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