Nevertheless, there was a nonsignificant trend toward increasing nAb levels in OTS‐300‐immunized animals.
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Adapted Live SARS-CoV-2 Vaccine Elicits Rapid Mucosal Immunity, Protects From Disease, and Reduces Shedding of XBB.1.5.
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For example, 2dpc, mock‐vaccinated animals showed a trend toward upregulation of RIG‐I , ISG‐15 , and CXCL‐10 in the nose (Figure 4c,d ) and significantly upregulated expression in the lungs compared with OTS‐300‐vaccinated animals (Figure 4e,f ; Figure S5a ).