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Impact of Clear Aligners on the Oral Microbiome: A Systematic Review of Current Evidence.

Clin Exp Dent Res · 2026 · PMC13140846 · PMID 41849703

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an adverse trendno p-value reported
This result indicates that usage of aligners for 12 h or more creates an adverse trend for an acid‐induced demineralization environment.

also in 37 other papers

an increasing trendno p-value reported
In the clinical parameters, PI showed an increasing trend during the 6‐month treatment in patients wearing FA but remained stable in patients wearing CA (Kaklamanos et al. 2023 ).

also in 33,188 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.