Localized delivery of hyaluronic acid-doxorubicin from a surgical paste for post-operative glioblastoma treatment.

Mater Today Bio · 2026 · PMC13142020 · PMID 42093737

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

approached significancep = 0.07so close (0.05 < p ≤ 0.1)

Although we did not observe a significant difference, the reduction compared with the paste-DOX treatment approached significance (p = 0.07), suggesting an improvement following HA conjugation.

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a decreasing trendno p-value reported

Similarly, CD133+ cells displayed a decreasing trend in number following treatment with paste-HA-DOX in our study.

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