Efficacy and Safety of a Defined Two-Dose Protocol of Autologous Platelet-Rich Plasma (PRP) Injection for Refractory Chronic Non-Healing Wounds: A Prospective Clinical Study.

Int Wound J · 2026 · PMC13143358 · PMID 42086201

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.3870

boldest claim

The sentences

highly significantp = 0.001actually significant

The most significant overall change was observed at Week 15 (12 weeks post‐second injection), yielding a high t‐statistic of 4.150 and a highly significant p value of p = 0.001.

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a positive trendp = 0.088so close (0.05 < p ≤ 0.1)

Venous Ulcers Notably, our venous ulcer subgroup showed a positive trend ( p = 0.088), mirroring evidence that PRP significantly reduces ulcer area within 30 days [ 29 ].

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did not reach statistical significancep = 0.387not close (p > 0.1)

However, this reduction did not reach statistical significance ( p = 0.387).

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