miR-99b-5p inhibition drives apoptosis and tumor shrinkage in triple-negative breast cancer: functional characterization through AGO2-RIP-seq and mechanistic insights.

Front Oncol · 2026 · PMC13143733 · PMID 42100432

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a decreasing trendno p-value reported

did not reach statistical significanceno p-value reported

At the protein level, inhibition of miR-99b-5p in MDA-MB-231 cells resulted in a statistically significant upregulation of DR5 and BAK1, while BCL-XL expression exhibited a decreasing trend that did not reach statistical significance ( Figure 2D ).

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