IL-17RA signaling promotes the dedifferentiation of Paneth progenitors through ADAM17 to regenerate gut epithelium post-irradiation.

Nat Commun · 2026 · PMC13144450 · PMID 41844615

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

a strong trendno p-value reported

While RT-qPCR analysis of regenerative markers within the terminal ileum yielded no significant differences between irradiated Adam17 fl/fl ;Defa6-cre + /− mice, we did see a strong trend towards decreased Nox1 expression in Adam17 fl/fl ;Defa6-cre + mice (Fig. 7F ).

also in 5,725 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.