Efficacy of 1064-Nm Picosecond Nd: YAG Laser in Treating Facial Photoaging and Improving Skin Barrier Enhanced by a Multi-Beneficial Composition Formulation: A Blinded Randomized Clinical Trial Study.

J Cosmet Dermatol · 2026 · PMC13144715 · PMID 42087413

Europe PMC DOI

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did not reach statistical significanceno p-value reported

At T57d, although intergroup differences did not reach statistical significance, sum scores on the test sides were consistently lower than those on the control sides across photoaging signs, suggesting an overall better skin status on the test sides.

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a decreasing trendno p-value reported

Both of these showed a decreasing trend over 56 days.

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