Apohemoglobin-haptoglobin complex is a therapeutic against vaso-occlusive crisis: scavenging of hemoglobin and heme.

Blood Adv · 2026 · PMC13146542 · PMID 41564434

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did not reach statistical significanceno p-value reported

HbSS mice without treatment had a significantly higher index (0.097 ± 0.024, P < .05), whereas Hp-treated (0.090 ± 0.022) and ApoHb-Hp–treated (0.077 ± 0.015) mice exhibited moderately increased values that did not reach statistical significance.

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