Barely Significant
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Antibiotic Stewardship: Comparing Meropenem De-Escalation and Continued Therapy When Cultures Show No Multi-Drug Resistance.

Cureus · 2026 · PMC13148116 · PMID 42099346

2
hedged sentences
0.1820
closest p · 3.6× alpha
0.1820
boldest claim

The sentences

did not reach statistical significancep = 0.182not close (p > 0.1)
Although mortality was numerically lower with de-escalation, this difference did not reach statistical significance (p = 0.182) (Figure 1 ).

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a numerical trendno p-value reported
Results: No statistically significant difference in mortality was observed (p = 0.182), although a numerical trend toward lower mortality in the de-escalation group was noted.

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