Licochalcone E Ameliorates Hepatic Steatosis in Obese Mice by Activating the Sirt1/AMPK Pathway and Reducing Hepatic Lipid Accumulation.

However, quantitative analysis of Oil Red O staining showed that, compared with the 5 μM LE/OA group, co-treatment with 5 μM LE plus 10 μM Compound C tended to increase lipid accumulation, although this difference did not reach statistical significance ( p =0.062) ( Fig. 3B ).

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