Abi3<sup>S212F</sup> Alzheimer's disease variant alters plaque structure and disrupts microglia.

Although total Aβ volume (measured by OC antibody for Aβ fibrils) remained unchanged or showed a trend toward an increase, there was a robust and significant reduction in Thio‐S+ dense‐core plaque volume in both the cortex and subiculum (Figure 3D–G ).

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