Genetic burden across core genes of the PI3K-AKT-mTOR pathway is associated with susceptibility to microscopic polyangiitis: a Chinese cohort study.

Front Immunol · 2026 · PMC13149408 · PMID 42112355

Europe PMC DOI

hedged sentences

0.0004

closest p · 0.0× alpha

0.0900

boldest claim

The sentences

highly significantP = 4.5×10 -4actually significant

A highly significant global association was detected in female participants (global P = 4.5×10 -4 ), whereas no evidence of a comparable association was observed in males.

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did not reach statistical significanceP = 0.09so close (0.05 < p ≤ 0.1)

55%), although this difference did not reach statistical significance (χ2 test, P = 0.09).

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