Dysbiosis of gut microbiota and metabolomic alterations in myasthenia gravis: insights from 16S rRNA sequencing and untargeted metabolomics.

Front Immunol · 2026 · PMC13149435 · PMID 42112324

Europe PMC DOI

hedged sentence

0.3540

closest p · 7.1× alpha

0.3540

boldest claim

The sentences

did not reach statistical significanceP = 0.354not close (p > 0.1)

The mediation analysis revealed that for the Ruminococcus → butanoic acid → QMGS pathway, the indirect effect was 0.106 (95% CI: −0.140 to 0.401), which did not reach statistical significance ( P = 0.354), likely due to the modest sample size and the near-zero total effect of Ruminococcus on QMGS (c = 0.017).

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