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Dual-targeted liposomes delivering ginsenoside CK attenuate cerebral ischemia-reperfusion injury by suppressing PANoptosis via O-GlcNAcylation of RIPK1/RIPK3.

J Ginseng Res · 2026 · PMC13149903 · PMID 42112134

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Notably, ginsenoside CK treatment showed some reduction in infarct volume, but this reduction was less pronounced and did not reach statistical significance compared to the LP/RTG and LP/RG groups, indicating that the liposomal formulation enhances the protective effects of ginsenoside CK ( Fig. 4 B and C).

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