Methodology for human-induced pluripotent stem cell-derived excitatory and inhibitory neuron coculture with astrocytes for Alzheimer's disease modelling.

Interestingly, both pyramidal cells and interneurons from APP V717I cultures showed a trend towards increased firing compared with isogenic controls ( P = 0.05412); however, no significant interaction was observed between current and genotype at the current sample size ( P = 0.1058) ( Fig. 6A and D ).

also in 53,322 other papers