Circulating Sphingomyelins Correlate With Plasma T-Tau in Cognitively Unimpaired Older Adults at Risk of Developing Alzheimer's Disease.

J Neurochem · 2026 · PMC13156478 · PMID 42104655

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did not reach statistical significanceno p-value reported

Although these trends did not reach statistical significance, the markedly lower scores—approximately half of those in amyloid‐negative individuals—may reflect subtle emerging cognitive vulnerability.

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