Causal and shared genetic insights into severe COVID-19 and idiopathic pulmonary fibrosis.

iScience · 2026 · PMC13156648 · PMID 42111219

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did not reach statistical significanceno p-value reported

9 , 24 , 25 In addition to presenting substantial evidence of a shared genetic architecture, our MR analysis confirmed a strong causal relationship between genetic susceptibility to IPF and severe COVID-19, establishing IPF as a risk factor for severe COVID-19; however, the reverse association did not reach statistical significance.

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