Comparison of IBD-related outcomes in patients with obesity treated with GLP-1 receptor agonists versus bariatric surgery.

16 Additionally, a matched case-control study of 25 patients with IBD who underwent BS (median follow-up, 7.69 years) demonstrated numerically lower rates of rescue corticosteroid use (24% vs 52%; OR 0.36, 95% CI, 0.08-1.23) and IBD-related surgery (12% vs 28%; OR 0.20, 95% CI, 0.004-1.79) compared with matched controls, although these differences did not reach statistical significance. 17 In addition to efficacy outcomes, we evaluated the incidence of GLP-1 RA-related gastrointestinal adverse events and the need for surgical intervention in patients with obesity and IBD.

also in 111,027 other papers