Barely Significant
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Association Between Baseline Depressive Symptoms and Clinical Characteristics, Biomarker Profiles, and Clinical Outcomes in Patients With Peripheral Arterial Disease Undergoing Revascularization: A Prospective Cohort Study.

Cureus · 2026 · PMC13158713 · PMID 42124738

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Although differences in individual endpoints, such as major amputation and mortality, did not reach statistical significance, likely due to limited statistical power, the consistent direction of effect across endpoints supports a potentially clinically relevant association.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.